![]() Don’t take an extra one to make up for it. If you forget to take your tablet, carry on as normal the next day.This is except for atorvastatin and rosuvastatin which you can take at any time. That’s because the liver is more active in making cholesterol at night. Your doctor or nurse might suggest you take your statins at night, before you go to bed.Take your statins every day to keep your cholesterol levels down.PS: If you haven’t yet, you can subscribe to my videos for free by clicking here and watch my full 2012 – 2015 presentations Uprooting the Leading Causes of Death, More than an Apple a Day, From Table to Able, and Food as Medicine. Anti-Angiogenesis: Cutting Off Tumor Supply LinesĪnd another video on the risks associated with taking estrogens: Plant-Based Bioidentical Hormones. ![]() If you don’t want to give up your grapefruit, you can ask your doctor about switching from a grapefruit-affected drug like Lipitor to one of the citrus-proof alternatives (the replacement drug chart can be seen in my video, Tell Your Doctor If You Eat Grapefruit). ![]() The Harvard Nurses’ Study even found a decreased risk of the scariest breast cancer type, so it doesn’t look like we have to worry about grapefruit affecting our natural chemistry.įor those prescribed unnatural chemistries, it may be a good idea to discontinue grapefruit consumption for 72 hours before use of a drug that may interact with it. If suppressing our drug clearance enzymes with grapefruit juice elevates levels of ingested estrogen, what might it be doing to our own estrogen levels? A study associating grapefruit consumption with breast cancer freaked out the medical community, but subsequent studies on even larger groups of women found no evidence of a link. Taking the Pill with grapefruit juice may increase blood drug concentrations by 137 percent. Women taking the Pill are normally at a higher risk of blood clots, but even more so, perhaps, if they have been consuming grapefruit. This may actually be good if we want a better caffeine buzz from our morning coffee, or our doctors want to help us save thousands of dollars by boosting the effects of expensive drugs instead of just peeing them away.īut higher drug levels may mean higher risk of side effects. Grapefruit is the poster child, described as a “pharmacologist’s nightmare.” Natural phytochemicals in grapefruit suppress the enzymes that help clear more than half of commonly prescribed drugs, and less drug clearance means higher drug levels in the body. If we eat lots of fruits and vegetables, we hopefully won’t need a lot of drugs ( Say No to Drugs by Saying Yes to More Plants), but certain phytochemicals in plants can affect the metabolism of drugs in the body. While grapefruits alone don’t have any side effects, ironically, combining grapefruits and drugs can make drug side effects even worse. To prevent heart disease, we really have to get down to a total cholesterol of around 150, which is the average cholesterol of those eating diets composed exclusively of plant foods, not just grapefruits (See, for example, One in a Thousand: Ending the Heart Disease Epidemic).Įven though grapefruits alone don’t do much, the researchers suggest that people might be more likely to stick with them than cholesterol lowering drugs, noting that most people with heart disease stop taking their statin drugs within a couple years because of the adverse side effects (see Statin Muscle Toxicity). For example, one study showed a decrease in cholesterol, but only from one life-threatening cholesterol level to another life-threatening cholesterol level. Other studies have found a legitimate cholesterol-lowering benefit of grapefruit, and even a little dip in triglycerides, especially eating red as opposed to white. That made me do a little double take, but again, it’s because the grapefruit didn’t do any better than placebo. They concluded that consumption of grapefruit daily for six weeks does not significantly decrease body weight, cholesterol, or blood pressure, though. The researchers reported that grapefruit consumers had a drop in weight, a significant drop in cholesterol, and a significant drop in blood pressure. So this belief that grapefruit has some special fat-burning quality appears to be just a long-held myth. If, however, we repeat the experiment and instead ask people to drink a half cup of water before each meal, we get the same result. In one study, the grapefruit eaters not only saw their weight go down, but their waist got slimmer, and their body fat melted away. If someone eats half of a grapefruit three times a day before each meal for a couple months, they may lose about two pounds - but that’s no more than if they ate three apples or pears a day. Does grapefruit in particular help people lose weight?
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![]() You are then able to roam around freely on the battlefield-cluttered with hundreds of individual soldiers, archers, and cavalrymen-and dispose of their enemies in close combat. The battles in Kessen II are instantly more interactive when compared to the original game, as they let you assume direct control of any of your generals by using the analog stick and face buttons. Koei has achieved those goals on both counts. However, this change is an intentional one on Koei's part, as the game's creators were more concerned with allowing you to enjoy the battles themselves, as well as make the game more accessible for novice players. The battle preparations in the original Kessen were much more involved, as they required both strategy and troop management on your part. For example, at the beginning of each battle, Liu Bei's generals present you with three basic options for troop positioning and movement-once an option is selected, the battle begins. Thus, you don't have to pay much attention to the story.įurther aiding those goals, the strategizing prior to the battles is now simpler and essentially laid out for you. ![]() Unlike the original game, which could be played as a straight war simulation, Kessen II is closer to the Koei's vision of creating a dynamic and interactive movie experience with its Kessen games. Each battle is sandwiched by lengthy cinematics, which essentially means that the game demands patience from the player and naturally requires a healthy interest in the Romance of Three Kingdoms epic. Kessen II's storyline is more robust than the original game's, so Kessen II is heavily driven by its plot, using both real-time and prerendered cutscenes. However, once Liu Bei engages Cao Cao's troops, he soon realizes that there is a much broader goal at hand, as he must secure the mandate of the heavens and save China from Cao Cao's tyranny. The primary story of Kessen II is about lost love, as the game's lead protagonist Liu Bei wages a seemingly desperate battle against a vicious warlord of the Wei Kingdom, Cao Cao, in a quest to rescue a woman named Diao Chan. The result is a game that is visually striking, with massive spell effects and a histrionic storyline, but one that may not appeal to fans of realistic war simulations. ![]() While Kessen was set in the Samurai era in Japan and based on a realistic premise, Kessen II centers on the Chinese Romance of the Three Kingdoms epic and is rooted more firmly in a fantasy setting. In Kessen II, Koei takes yet another step toward achieving more general appeal for its historical strategy games. But the original Kessen for the PlayStation 2 was a giant step forward for the company, as it moved Koei's historical simulations into the real-time 3D world and appealed to a broader audience. The game contains 10 stages of battles in all, five for each side.Koei, the developer of such turn-based strategy games as The Romance of the Three Kingdom series, has added something unique to the genre: You are able to bribe members of the opposite side to come and join your team, so if there is a certain general that would look good working for you, just click on him and see what happens.The game's turn-based strategic combat is surrounded by real-time cutscenes that move along the cinematic story, which is filled with personal conflict and political intrigue.For years, the historical strategy genre has been Koei's bread and butter, but over time, the appeal of classic series such as Nobunaga's Ambition and Romance of the Three Kingdoms became limited to a niche audience. Kessen boasts two different modes: the story mode, where you control either army, and a hidden battle mode where you can jump back into any previous battle and try your luck again or plan a different strategy to try and win the war. Tokugawa Ieyasu is a very strong and powerful leader and is tired of seeing the country ruled by his archenemy, Toyotomi Hideyoshi.This is a single player tactical strategy game where you take control of either side to decide the fate of Japan for years to come. ![]() This is the setting for Kessen by Koei and Electronic Arts for the PlayStation 2.Kessen is the story of two warring clans waging war against each other for control of the entire land, during 15th and 16th century Japan. Let us go back to feudal Japan, where a few good men lived by the sword and died by the sword. Let us take a step back through time - to a place where honor meant everything. |